Grey's Anatomy

New York & Company, Inc., a specialty clothing chain, announced that it will be spearheading its Fall 2006 marketing campaign with a couple of familiar faces: Ellen Pompeo and Patrick Dempsey.

The stars, who have captivated millions with their portrayals of Drs. Meredith Grey and Derek "McDreamy" Shepherd on Grey's Anatomy, will be featured in a campaign that showcases their undeniable chemistry (as well as the company's striking fall line of apparel).

"The big difference between shooting a couple that knows one another versus hired models is they already have a working relationship," a New York & Company executive said. "Patrick is very charming and funny. He's a one-stop source of one-liners. Ellen was trying to concentrate so hard on getting the right shot, and he kept cracking her up. There was such great energy the whole day."

No, Pompeo did not don any blue scrubs for the shoot. Rather, she posed in 16 different outfits, including the company's signature perfect fit pants, which are individually custom-tailored to a woman's body and proportions. In Ellen's case, that would be rather thin! But in a good way, of course.

Pompeo was also photographed in an array of tailored tops, as well as '80s-influenced, long-waist sweaters... one of which (wait for it) happened to be in a light grey.

New York & Company approached the pair about the shoot, which took place recently in East Hampton, N.Y., before the outcome of season two had been revealed. It was a gamble that paid off.

"Our customer is very invested in TV, what's going on, who's hot. Nothing's hotter than Grey's Anatomy, and that's why Ellen and Patrick were such a perfect fit. All of America is waiting for them to get together and we guessed that the season would end the way it did," the exec said.