The man behind McDreamy on Grey's Anatomy opens up to the magazine about choosing family-friendly roles, coping with success at such a young age, and keeping his marriage on track. Below are some excerpts:
On making his wife, Jillian Dempsey, swoon:
"I hope I still make her swoon! Sometimes I think to myself, God, would Derek Shepherd do this? Because I am certainly not a perfect male at this moment. Just trying to provide and communicate and let her know how beautiful and important she is to me - I think those things make her swoon."
On returning to romantic comedies:
"I don't want to do violent movies right now because I think there's too much violence in the world and I don't want to add to that. Romantic comedies, at this point - we're at war, we're in a horrible place worldwide - I want to so something that is going to help people escape. Enchanted was a movie I did for my daughter [Talula, 5]. I wanted to do something that kids can go see, and is fun for adults as well.
On his first shot at stardom:
"Mentally, I never really wanted success until I was in my 30s. Quite honestly, I think I sabotaged myself in my 20s because I felt I was too young and didn't realize what was happening. But there was a time when I didn't think it was going to work out. Like, wow, maybe that was the best period in my life."