Part of the Bruno Kirby Celebrity Reading Series, Gary Blumsack will direct the event, scheduled for August 20 at 8 p.m.
Canal Street casts Mazursky as "Milton, an ornery and abrasive nursing home resident with questionable mental faculties who is paid a surprise visit by a young woman (Wilson) claiming to be his daughter."
"The two engage in a sparring match of wits and wisdom. Will they let their differences keep them strangers or can they become a family?"
Wilson â€" currently nominated (a second time) for her turn on ABC's Grey's Anatomy â€" earned a SAG Award for that role.
In the past, Chandra Wilson appeared onstage in Caroline, or Change as well as in The Good Times Are Killing Me, Paper Moon: The Musical, The Family Mann and the George C. Wolfe-directed Broadway revival of On The Town.
Mazursky is known for his work as a director on such films as Bob, Carol, Ted & Alice, Blume in Love, Down and Out in Beverly Hills, The Tempest, Harry and Tonto, An Unmarried Woman and Moscow on the Hudson.
As an actor, he has appeared in A Star Is Born, Carlito's Way and Love Affair as well as in TV's Once and Again and Curb Your Enthusiasm.