Pictures From "A Change is Gonna Come"

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The new interns have arrived. Meredith meets her sister and Cristina can't find Burke. Lexie is, in fact, spelled with an e. Former Grey's stars Isaiah Washington (Bionic Woman) and Kate Walsh (Private Practice) will very soon be going up against each other for ratings on Wednesday nights.

A lot has changed, and this promises to be an interesting fall at Seattle Grace and beyond, that much is for sure. In preparation for the big night, we've put together a gallery of photos we found for the season premiere, "A Change is Gonna Come," which premieres two weeks from Thursday (September 27).

Meredith Looks Distraught

Follow our link to see the gallery from the Season 4 premiere. Don't click on it if you don't want anything spoiled, although the photos we have don't tell us much that we don't already know. As always, you can discuss the upcoming episode (and anything related to the show) in our forum. Enjoy!

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hello from sunny greece-cete island..
i watch u every night
i am addicted!!!!and cos of me...1000more people..xixixixi
many many kisses


I can't stand Izzie because to me she is to poor me, help me, I'm a whore!!!! Sorry people but I like Callie because she is real and if I was her I would hook back up with Mac Steamy because he is way better then George!!!!!!!!! Also I don't understand how Izzie could be so in love with Denny then when he dies and George get's married all of a sudden she loves George!! If I was George I would be like it's to late you could of had me before so why do you want me now!!! To much to say about this but lets end it with Callie go ahead and do your thing with Mac Steamy because his more on your level than George!!!!


marina i agree with you
izzie and george are good together
i want izzie to be pregnat instead of callie, she doesn't deserve george and george doesn't deserve to have to repeat his internship he doesn't need callie and should just leave her for izzie.


Thanks for your comment Kathy, it really is reassuring that Der / Mer will be ok in the next season. I cant wait to see them progress as a couple and I would love to see more of them outside the hospital.


I noticed in the clip of Patrick on EXTRA, that he made a very important comment that I picked right up on.....he was asked about the way the season ended with him pouring his heart out to Meredith...what was going to happen and his comment was"we basically pick up where the conversation left off and they continue working through things to progress with their relationship"!!!
That is GREAT News for us Mer/Der fans! That sure sounds to me like things are going to be ok with Mer/ may take a few epsiodes, but thats ok as long as we know they will be together!


I want Callie and george to divorce stat and for him and Izzie to get together. I like Lexie from her sneak peeks, she seems so sweet, and not at all after Derek. She didn,t even recognize him, McDreamy my eye, LOL. I hear she will be paired with Alex and become friends with george, maybe he can help her with Mer, since she will be his resident. But I really really want George and Izzie together, I love them SO much


God, I hope not. I hated Alex and Izzie more than anything in the world. She and george are so much better. I hear Alex and Ava sleep together and then he gets with Lexie, so pretty sure the Alex and Izzie stuff is nt happening this season at least, thank you God! Right now, I watch for Meredith and Derek and George and Izzie, the two best couples on TV. Also want to know how george deal with failing his internship.


I really missy Izzie and Alex as a couple, they could have been so good together! I hope at some point they'll get another chance at it!



Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.


Doesn't matter how tough we are, trauma always leaves a scar. It follows us home, it changes our lives, trauma messes everybody up, but maybe that's the point. All the pain and the fear and the crap. Maybe going through all of that is what keeps us moving forward. It's what pushes us. Maybe we have to get a little messed up, before we can step up.

Alex (narrating)