Eric Dane to Star in New Movie

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Grey's Anatomy cast member Eric Dane has taken a co-starring role alongside Owen Wilson, Jennifer Aniston and Alan Arkin in Marley & Me.

The feature film - the first for Dane since X-Men United - is an adaptation of John Grogan's bestselling memoir. David Franklin is directing.

Mr. & Mrs. Eric Dane

Mr. and Mrs. Eric Dane (also known as Rebecca Gayheart).

Owen Wilson plays the ambitious reporter who moves with his wife (Aniston) to Miami for a newspaper job. Eric Dane will play the journalist's best friend, who suggests that the reporter adopt a puppy as a substitute for the children his wife wants to have.

Marley, of course, is an adorable Lab puppy but an incorrigible handful.

We're looking forward to Dane's big-screen return in Marley & Me.

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Dane, We all new you had it in ya. It's so cool to watch an old bro of mine on t.v. and follow the hype on you. Your killing it bra, your boy, Ian

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I am so stocked to see my man heading to the big screens. Now I can remove x-men the last stand from my dvd player[lol]. Congrats to Eric. Hope this movie does wonderful things for his career.

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Congrats Eric!! It's about time you crossed over to the big screen!

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If this film sticks to its expected release date (Dec. 2008), I just got my early Christmas present. Happy to see Eric is getting the opportunity to work on a film that comes from a respected book. This a good opportunity for him to show that he is more than just McSteamy.

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith