Eric Dane to Star in New Movie

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Grey's Anatomy cast member Eric Dane has taken a co-starring role alongside Owen Wilson, Jennifer Aniston and Alan Arkin in Marley & Me.

The feature film - the first for Dane since X-Men United - is an adaptation of John Grogan's bestselling memoir. David Franklin is directing.

Mr. & Mrs. Eric Dane

Mr. and Mrs. Eric Dane (also known as Rebecca Gayheart).

Owen Wilson plays the ambitious reporter who moves with his wife (Aniston) to Miami for a newspaper job. Eric Dane will play the journalist's best friend, who suggests that the reporter adopt a puppy as a substitute for the children his wife wants to have.

Marley, of course, is an adorable Lab puppy but an incorrigible handful.

We're looking forward to Dane's big-screen return in Marley & Me.

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Dane, We all new you had it in ya. It's so cool to watch an old bro of mine on t.v. and follow the hype on you. Your killing it bra, your boy, Ian

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I am so stocked to see my man heading to the big screens. Now I can remove x-men the last stand from my dvd player[lol]. Congrats to Eric. Hope this movie does wonderful things for his career.

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Congrats Eric!! It's about time you crossed over to the big screen!

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If this film sticks to its expected release date (Dec. 2008), I just got my early Christmas present. Happy to see Eric is getting the opportunity to work on a film that comes from a respected book. This a good opportunity for him to show that he is more than just McSteamy.

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Grey's Anatomy Quotes

[narrating] "At some point, you have to make a decision. Boundaries don't keep other people out, they fence you in. Life is messy, that's how we're made. So you can waste your life drawing lines or you can live your life crossing them. But there are some lines that are way too dangerous to cross. Here's what I know. If you're willing to throw caution to the wind and take a chance, the view from the other side... is spectacular."

MEREDITH

[narrating] The human life is made up of choices. Yes or no. In or out. Up or down. And then there are the choices that matter. Love or hate. To be a hero or to be a coward. To fight or to give in. To live. Or die. Live or die. That's the important choice. And it's not always in our hands.

Derek