Happy Birthday, Patrick Dempsey!

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The undisputed leading man of Grey's Anatomy, Patrick Dempsey, turns 43 today. Happy birthday, Patrick! The Maine native first rose to fame so long ago, many Grey's Anatomy fans probably aren't even familiar with what the star used to look like:

Young Patrick Dempsey

Hey, it was the late 1980s. We forgive McDreamy for the hair. While he was always a successful working actor, his second turn at stardom came early in 2005 when Derek Shepherd woke up in Meredith Grey's bed in the Grey's Anatomy pilot.

What a great ride it's been since.

Here's a little photo gallery of Patrick in honor of his big day. Click to enlarge!

Hunkiest TV Star Ever!
Patrick Dempsey Rides
What a McDreamy Individual
Too Sexy
A Pair of Stars
Young Pat
Senor Suave
Cover of E-Dubs
A Patrick Portrait
Race Car Drivin'
A Young Stud
Patrick & Jillian Dempsey at the Emmys
Sad Shepherd
Patrick & Jillian Dempsey
Patrick: Life Cover
It's Twins!
Patrick Dempsey Versace Ad
Jillian and Patrick Dempsey
Man of the Hour
Old Friends Again?
Hotness
Best Looks Ever
And Some MerDer Love Too
So, Come Here Often?

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Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Happy birthday Patrick! You are like wine, the older, the better ♥

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Happy birthday!

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Happy Birthday Late
I have been a fan of yours for a long time. I also am an Avon Representative and is very excited about having your wife Jillian working with Avon. Congratulations also on your twins. That must keep you both very busy. God bless you.

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Feliz aniversario Patrick,voce é igual ao vinho,quanto mais velho melhor.Parabens!

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Happy Belated Birthday you sexy man!
I love McDreamy, amazing actor, keep up the good work!
Love you!

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For the photo:terrific hair!

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Happy birthday to the sexiest Capricorn on the planet.

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HAPPY BIRTHDAY MCDREAMY!!!!!!!!!!!!
i hpoe you feel better & healthy all the time!
YOU'RE AWESOME & GREAT! and what are your plans at 2009? AND BE THE HOTNESS GUY!!!!!

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HAPPY BIRTHDAY MCDREAMY!!!
I

Merder4ever

HAPPY (belated)BIRTHDAY PATRICK!! Another year and up another degree on the hotness scale! Stay beautiful!

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old, in your arms. I don't want 48 uninterrupted hours. I want a lifetime. Mmm. Do you see what happens? I say things like that and you fight the urge to run in the opposite direction. It's okay, I understand. I didn't, but now I do, I do. You're just getting started and I've been doing this for a long time now. Deep down, you're still an intern, and you're not ready.

Derek