How will the second half of this season play out on House?

TV Guide asked that question of executive producer Katie Jacobs. She proceeded to weigh in on issues such as the presence of Thirteen, about whom Jacobs said:

"People hate change, they hate new things."

However, the producer urged fans to stay tuned "because it's a marathon."

Also check out the video below to hear what Jacobs has to say about new mother Cuddy, as well as possible scoop her future with House...

Matt Richenthal is the Editor in Chief of TV Fanatic. Follow him on Twitter and on Google+.