Grey's Anatomy Preview: "What a Difference a Day Makes"

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Next Thursday, Grey's Anatomy turns 100 episodes young with a blockbuster wedding event. But will the long-awaited union of Meredith and Derek go off without a hitch?

Here's a preview of the episode, entitled "What a Difference a Day Makes." Despite her undying love for McDreamy, Mer is a little nervous about walking down the aisle ...

[video url="http://www.greysanatomyinsider.com/videos/what-a-difference-a-day-makes-sneak-preview-1/" title="What a Difference a Day Makes Sneak Preview #1"] [/video]

Elsewhere, Izzie's condition is bad, and getting worse. She's even experiencing familiar symptoms. Handsome symptoms, if you know what we mean. Know what we mean?

If not, click here for more preview clips ...

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Grey's Anatomy Quotes

[narrating] "At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing where we all keep our distance and pretend not to care about each other, it's usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them. The people that are still with you at the end of the day, those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need."

MEREDITH

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)