TV Guide has a brief note on Grey's Anatomy in its weekly spoiler Q&A today. Nothing really new here, but still, worth sharing. Here's what they have to say:

Q: So sad that T.R. Knight (George O'Malley) is leaving Grey's Anatomy. What can you tell me about the big sixth season premiere Thursday, September 24?

A: While pretty much everyone at Seattle Grace is shaken by George's departure (and in some cases very shaken), Derek somehow keeps it together. That might be because McDreamy's got something bigger on his mind: the promise of becoming the next chief of surgery.

What do you think? Will Derek take over as Chief? Should he?

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.