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Grey's Anatomy Spoilers: New Blood, New Beginnings

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Today's TV Guide spoiler Q&A focuses on a question many of us have been asking throughout the offseason as a "transitional" Grey's Anatomy begins to take shape: How will things change with some of its mainstays out of commission for significant periods of time?

Here's the latest dish on that, plus a bonus Private Practice item ...

Q: How will Grey's Anatomy write around the absences of Ellen Pompeo and Katherine Heigl?

A: The show will shift its focus to more character-centric episodes, executive producer Krista Vernoff says. One hour will be almost exclusively dedicated to Derek and a patient.

Seattle Grace's merger with Mercy West will bring in some new blood and cut loose some long-standing characters. Specific fallout from that plot line? That we'll have to wait for.

Bailey's in Charge

"There are some that stay [and] some that don't make it," says Chandra Wilson.

"There will be some familiar faces that remain ... but we also wanted the audience to be able to feel that this is a huge thing and that there was a loss there."

Q: Will Addison get a new love interest this season on Private Practice?

A: Kate Walsh answers this one: "I think we're holding off for a while," she says. "[Shonda Rhimes] is really interested in just seeing Addison single and running the practice with Sam." But that means more scenes with Taye Diggs - and more Taye Diggs is always a good thing, right?

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Well I like Lexie. I think shes cute and funny. Shes a much more relatable character.

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More McSteamy please and without Lexie. Her character is sooo boring and annoying. I would be happy to see her as one of the characters that gets lost in the new merge with Mercy West!

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Telania, So far, no other actor has been fired but characters will be laid off (Izzie for one) while SGH deals with the merger and economic issues. Doesn't mean that they'll no longer be on the show. Jessica, ABC has the full episodes (if you are in the USA) but other websites like surfthechannel.com, ch131.com, and others have it also online. Callie turns 'bi' in late season 4. And Meredith is the main character, not George or Izzie.

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Sorry to admit but I just started watching GA on lifetime i think yesturdays episode was when izzy and mer thoguth that callie didnt wash her hands i think her name is callie i missed the episode where she came in and she confuses me and being this new to everything i dont know when she turns bi or whatever (not discriminating) if anyone would eb willing to give me a website or something to catch me up i would love it got my timer set for tonights episode I'm pretty anxious I personally hate that george is leaving, don't see how they can be without the MAIN character, or how they can make izzy survive and then not have her on the shows??

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I don't get it. Will other actors be fired? What do they mean, other losses?

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Dimples, Bizzy is Addie's mom. In PP, the first time Archer visited Addie, they talked about how Bizzy didn't allowed Addie or Archer to call her mom. :)

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I can't wait till Bailey goes to LA to see Addie. That is going to be awsome. Maybe she will flirt a little with Sam. LOL!!! I hope for some reason she gets to fuss at them as only Bailey can fuss. LOL!!! I love Bailey AZ and Callie. But I like Mer Der and Christina and Izzy. Well I did like Sloan till be got nasty dating Lexie. And I think the chief is pretty cool.

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Who is Bizzy. Hmmm I missed something. I don't have any idea who that is. Wow I"m slipping. LOL!!!

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Exactly Angela. It also worked for other medical dramas and they need to keep the focus away for a while. Also, it is good to get to know other characters. I am actually quite excited for this Derek-centric episode. It's about time that the Attendings get a part of the action. Besides, I totally missed the part when it was said that Lexie was going to have an hour dedicated to her. If I'm not wrong, it's Derek and Bailey getting the character centric episodes. As for Addie, good for her. I do want to meet Bizzy. Addie got so little background on GA.

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Yup Sophie, well said! Something different: Ellen Pompeo gave birth to her daughter. I read that from several sources. Ellen and her hubbie named her Stella Luna- isn't it one of the cutest names ever? :))) just wanted you all to know this, wondered why ga-insider hasn't posted it yet..

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith
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