Grey's Anatomy is back tomorrow night with its first episode in three weeks and the first of five (counting the two-hour finale as two) to close out the current season.

What can we expect Thursday and beyond? Fancast reports the following ...

• On April: When the show returns tomorrow night, the Mercy Wester will be "as creepy as ever" – so much so that people will start noticing. Hmmm.

• On tomorrow night's episode: McSteamy becomes an actual grandfather. Meanwhile, Teddy’s vulnerable (and presumably bikini-waxed) side is revealed when her position is thrown into jeopardy, and things only get messier for Mark and Lexie.

• On the game-changing finale: “Seattle Grace Hospital is hit with a crisis like no other in its history,” after which “Cristina and Meredith’s surgical skills are put to the ultimate test.” Okay, that tells us nothing, but your theories are welcomed!

What can we expect from Lexie and April tomorrow?

Meanwhile, TV Guide has this to say about what by all accounts is an explosive season finale: "A multi-car pileup that floods Seattle Grace with victims. Meanwhile, one of hospital's doctors will also have to contend with a deadly fire in her home."

Shonda Rhimes says: "Fans should brace themselves. That's the only way to put it."

"Brace yourself. We're going to take you on a ride for the last two hours of the season, and when the ride is over, none of our characters are going to be the same."

"It's very different in comparison to the other finales."

Thoughts? Opinions? Comment away!

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.