Through various House spoilers and quotes, it's been made clear:
House and Cuddy will be involved in a real relationship on season seven of the Fox hit. The long-time friends/rivals gave in to their feelings on the May finale and will continue to do so when the drama returns on September 20.
The following promo makes this as clear as ever:
[video url="http://www.tvfanatic.com/videos/huddy-sex-alert/" title="Huddy Sex Alert!"] [/video]