Based on photos for the first Supernatural episode of 2011, we can confirm the presence of the following on this show's January 28 installment:
Now, The CW has released the official episode description for "Like a Virgin." It gives fans more of an idea of what they can expect when Sam and Dean return to the small screen:
Dean and Bobby anxiously wait for Sam to wake up to see if Death was able to restore his soul without causing Sam to lose his mind. Meanwhile, Dean and Bobby investigate a disappearance of virgins and discover dragons are behind the kidnappings. Bobby sends Dean to a doctor who owns the only weapon in the world that can slay a dragon, but Dean must prove himself worthy enough to take it.