Jessica Capshaw has always been prepared for a struggle.

Asked what we can expect after her character, Arizona, marries Callie on the May 5 episode of Grey's Anatomy (see Calzona wedding photos), she had an interesting response.

Capshaw said the show's take on love and relationships has always been unorthodox, and that struggling with the ones we love has been a theme since the very beginning.

"Shonda Rhimes and Betsy Beers have both talked about, since the inception of the show, Grey's Anatomy was never about commitment and marriage," the actress tells E!

The wedding will be blissful. But what about what comes after?

"It was always about loving someone you're not supposed to love. How do you figure that out? How do you then find your way to them? Do you say no? Do you go to them?"

"[The show used to be about] impossible relationships, possible relationships in impossible circumstances... but now I think it's sort of evolved and matured to what it is now."

"Its about how do you keep and nurture and drive in relationships. That being said, it's a one-hour drama, so you can't just have a bunch of really happy people."

"I'm just guessing now - this is just Jessica Capshaw guessing - I'm sure there will be fallout [from everything that's happened]. Last season Arizona didn't want kids."

"Now she has a kid. Does that mean Arizona is going to become the quintessential mother? Is she going to start baking cookies and having bake sales? I have no idea."

"But my guess is, she won't."

Interesting. Do you think Arizona will be cool to the idea of parenting in the traditional sense at first, or will she delve in faster than some people probably expect?

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.