It's the major news heading into this Friday's installment of Supernatural: James Marsters and Charisma Carpenter will guest star as husband and wife.

But the former Buffy the Vampire Slayer actors won't exactly be getting along, as teased in the following sneak peek at "Shut Up, Dr. Phil." Look for Carpenter's Maggie to take issue with Marsters' Don because he cheated on her. Oh, and Maggie is also a witch being hunted by Sam an Dean.

Feast your eyes on a clip from the episode now:

Matt Richenthal is the Editor in Chief of TV Fanatic. Follow him on Twitter and on Google+.