Nia Vardalos, Peri Gilpin to Guest Star on Grey's Anatomy

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My Big Fat Greek Wedding star Nia Vardalos and Frasier's Peri Gilpin will guest star on an episode of Grey's Anatomy, and portray sisters on the medical drama, according to The Hollywood Reporter.

Vardalos, whose TV work includes stints on Cougar Town, Drop Dead Diva and My Boys, will play Karen Winterbottom, while Make It or Break It's Gilpin will play her sibling, Marcy Winterbottom.

The bickering sisters will come to Seattle Grace in a mid-January episode.

Nia, Peri

Vardalos' casting comes nearly two weeks after Grey's and Cougar Town producer ABC Studios announced that it was developing a comedy for the actress, who is married to Cougar Town's Ian Gomez.

Gilpin, meanwhile, stars on ABC Family's Make It or Break It, but is probably best known as radio producer Roz Doyle, who kept Kelsey Grammer in line for 11 seasons on NBC's Frasier.

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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@holliez no they are not playing der's sisters actually says in the story who they are playing.

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Cant wait to watch the next episode pls air it asap....

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greys anatomy is back january 5th!

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Is there any possibilty that they could play Der's two sisters we haven't met yet?? It's just with their hair and eye colouring i could really see them as Der's sisters. This is just idle speculation on my part that's all

Smileyglen

Can't wait, these actresses certainly look like sister and I love their work and watching them together it will be funny for sure.

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