First, it was George O'Malley. Then, Lexie Grey. Most recently, Mark Sloan.

Who will fall next on Grey's Anatomy? Let the speculation begin now.

According to reports, in early 2013, someone else we know will die.

It's a longtime character, apparently, and one very much beloved.

That's all we have to go on right now, and clearly "longtime character" could mean many things. Who do you think is in danger this time? What circumstances do you think could bring about his/her demise?

Is there anyone in particular you would be crushed to see pass away in 2013, even though some of these arcs make for the most moving episodes? Conversely, whose death might make the most sense?

Share your comments, concerns and theories with us below ...

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.