Changes are coming to Mystic Falls.

In an interview with TV Guide Magazine, Executive Producer Julie Plec offered up some major clues regarding both The Vampire Diaries Season 4 finale and even gave us our first clues regarding where things are headed on The Vampire Diaries Season 5.

Teasing that graduation will fall "right in the middle of "a crucial supernatural time," Plec made one thing very clear about the storyline on which the past few months have been based?

That pesky cure?

It will "be ingested by a vampire. This will be one of the finale's final moments," the producer tells William Keck.

As for where seniors such as Elena, Stefan, Caroline, Matt, Bonnie and Rebekah will be headed after donning their caps and gowns?

Look for some to enroll at nearby Whitmore College, while others "may choose to run off to Europe, New Orleans or parts unknown," Plec previewed, a lot of which - we presume - is based on whether or not The CW picks up The Originals.

So, TVD Fanatics, sound off now: Which vampire do you think will take the cure?

Matt Richenthal is the Editor in Chief of TV Fanatic. Follow him on Twitter and on Google+.