Thursdays 8:00 PM on CBS
The-big-bang-theory

Sara Gilbert stars as Leslie Winkle, a physicist that works at the same Caltech lab as Leonard.  She has had an on-and-off again relationship with Leonard and is bitter enemies with Sheldon.

Leslie Winkle Quotes

I saw your pupils dilate when you looked at her, which, unless you're a heroin addict, points to sexual attraction

Leslie [about Leonard's interest in Penny]

Leslie: Just so we're clear, you understand that me hanging back to practice with you is a pretext for letting you know that I'm sexually available.
Leonard: Really?
Leslie: Yeah. I'm good to go.
Leonard: I thought you weren't interested in me.
Leslie: That was before I saw you handling that beautiful piece of wood between your legs