Lisa Grimaldi (née Miller) is a character on As the World Turns. The daughter of Henry and Alma Miller, Lisa grew up in Rockford, Illinois before moving to Oakdale.

The character first appeared in May 1960, as the fiancée of medical student Bob Hughes. (The two would soon elope, when they discovered that Lisa was pregnant). Over the next four decades, Lisa would go on to marry seven more times. A scheming "vixen" in her early years, Time magazine once referred to her as a "superbitch" and the "most hated woman on TV."

Since those days, Lisa has gone on to become a well-respected presence in Oakdale (the fictional town in which As the World Turns is set), often offering advice and support to the town's younger residents.

An entrepreneur, she currently owns a restaurant, a clothing boutique andhotel; she formerly owned one of the town's newspapers, The Argus, and a nightclub. She recently started work on Crash, a new teen-oriented music club, with the help of her grandson Casey.

The character briefly crossed over into her own prime time spinoff series, Our Private World, for a few months in 1965, during which Lisa left Oakdale and moved to Chicago. She returned to Oakdale in 1966.

She has two sons — a third son was killed in an automobile accident in the early 1970s — and four grandchildren. Since 1960, she has been portrayed primarily by Eileen Fulton.