Mark is best friends with Derek when he is happy and he is best friends with Callie when he is lonely & miserable. To me Mark brings out the worst in Callie & Arizona brings out the best in her. Just like Shondra said, Arizona and Callie are MFEO (Meant for Each Other) they are truely each others soul mates. They have a real and deep connection with each other that many people wished they had. Sara Ramirez was even quoted to saying "Arizona is the love of Callie's life". So why does it matter if it is a same-sex relationship? Love is love and that is something that we should all cherish.
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