The Winchester brothers appear to be waiting for something... or someone. So what does Sam see? The photos they give us for Supernatural usually take place within a ten minute time frame of the episode, so it's a guessing game!
Dean is looking really serious. Is he still running on some major Mark of Cain power? Honestly, Mark of Cain power is kind of cool, even if it's dangerous as hell. It will make for an amazing finale if that's what we're witnessing.