Callie and Arizona certainly qualify as that. Whether you believe they are really lesbians or not, the acting by Jessica Capshaw and Sara Ramirez is terrific.
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Calliope Torres has been disowned by her family, but she loves Arizona, and she loves her work. We think this talented doctor will be okay.
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Arizona and Callie are one of Grey's Anatomy's newest and most controversial couples. They're doing better lately, although there is always a crisis around the corner.
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Callie and Arizona (Calzona) at the wedding of Alex and Izzie. Having gotten over their nonsensical fight over Callie's money problems, the two are back on good terms.
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Callie and Arizona share a kiss in the church where the wedding took place. The people getting married where not who we thought, but the magic of the day was still palpable.
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Callie introduces Arizona to her dad. That's not gonna go well, we have a hunch.
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Callie (Sara Ramirez) and her father (Hector Elizondo) in "Sweet Surrender" from Season Five of Grey's Anatomy.
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Callie Torres (Sara Ramirez) is a terrific Grey's Anatomy character, even if the writers can't decide what to do with her sexual orientation.
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Grey's Anatomy Quotes

Just because we can live without something, it doesn't mean we have to.

Meredith

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith