Oh no! It looks like something has got Sam down. Is he hurt? Is it Death? Even Dean looks concerned. What the hell? Did Death attempt a death blow with that huge scythe? Didn't we already determine that wasn't an option?!
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Has Death come for Dean? Did the older Winchester brother make a dangerous deal? Be careful, Dean! Seriously, that's a pretty precarious position Dean is in, but just by being in it, we feel a little better, right?
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The Winchester brothers appear to be waiting for something... or someone. So what does Sam see? The photos they give us for Supernatural usually take place within a ten minute time frame of the episode, so it's a guessing game!
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Dean is looking really serious. Is he still running on some major Mark of Cain power? Honestly, Mark of Cain power is kind of cool, even if it's dangerous as hell. It will make for an amazing finale if that's what we're witnessing.
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Are Sam and Dean facing off? It certainly looks like an intense showdown between the two brothers. It's the season finale and we know pretty much anything can happen between these two at this point.
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Charlie tells Dean and Sam she has something that can remove the Mark of Cain on Supernatural. "Book of the Damned" is the 18th episode of the show's tenth season.
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Dean is looking for a way to cure the Mark of Cain and doing so with violence. Gulp.
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The Winchester Bros. are strolling around eating food.
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Supernatural Quotes

You're wrong. I am utterly indifferent to sexual orientation. On the other hand, I cannot abide hypocrites like you, Reverend. Tell your flock where your genitals have been before you speak for me.

Castiel

Do you ever get tired of urinating? I'll never get used to it.

Castiel