Given that smile on Derek's face, we hope that means good news for the patient on Grey's Anatomy.
With so much going on at work and at home, in the operating room is probably the place Derek feels most at ease on Grey's Anatomy.
There it is. There's that Derek Shepherd smile we've all grown to love.
Congrats to Cristina! She's been nominated for a Harper Avery!
The only couple on this list who actually hooked up prior to the series ever starting, Grey's Anatomy kicked off the morning after Meredith and Derek went home from a bar together. Sure, he was married at the time - but that technicality was no match in the end for (sorry we have to say it...) the McDreamiest pairing on all of television.
Whatever's going on, Derek looks very serious on Grey's Anatomy.
When someone falls to the floor, Derek and Owen fight to save a life in "Do You Know?"
It's like Derek is smiling into our soul in this Grey's Anatomy image, isn't it?
Unfortunately for McDreamy, Meredith may be the one person who isn't awed by his big news in "Take It Back"
Everyone wants Derek, even the President of the United States is giving him a call on Grey's Anatomy.
Derek gets an offer that could change everything on Grey's Anatomy. "Get Up, Stand Up" is the 12th episode of the show's tenth season.
Derek had to bring the baby in to work on Grey's Anatomy. "Get Up, Stand Up" is the 12th episode of the show's tenth season.

Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

Lexie: [narrating] Grief may be a thing we all have in common, but it looks different on everyone.
Mark: It isn't just death we have to grieve. It's life. It's loss. It's change.
Alex: And when we wonder why it has to suck so much sometimes, has to hurt so bad. The thing we gotta try to remember is that it can turn on a dime.
Izzie: That's how you stay alive. When it hurts so much you can't breathe, that's how you survive.
Derek: By remembering that one day, somehow, impossibly, you won't feel this way. It won't hurt this much.
Bailey: Grief comes in its own time for everyone, in its own way.
Owen: So the best we can do, the best anyone can do, is try for honesty.
Meredith: The really crappy thing, the very worst part of grief is that you can't control it.
Arizona: The best we can do is try to let ourselves feel it when it comes.
Callie: And let it go when we can.
Meredith: The very worst part is that the minute you think you're past it, it starts all over again.
Cristina: And always, every time, it takes your breath away.
Meredith: There are five stages of grief. They look different on all of us, but there are always five.
Alex: Denial.
Derek: Anger.
Bailey: Bargaining.
Lexie: Depression.
Richard: Acceptance.