That was the climactic scene of the 100th episode of Grey's Anatomy - the surprise nuptials of Alex and Izzie. Meredith and Derek were the ones supposedly getting married this day!
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Alex and Izzie are husband and wife.
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Alex, Izzie and George take orders from the Nazi.
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Alex comforts Izzie in her time of need.
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Or at least until two of them hook up and things are weird.
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So little time.
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Sorry. We're running out of Izzie Stevens puns.
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Isobel wonders where Alex is.
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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith