Meredith, Izzie and Cristina see an ambulance coming around the bend and heading straight for them... while they're trying to unload people and get them into the hospital. Looks like an episode for the ages.

Callie, Meredith, Cristina, Izzie and Miranda prepare for action as an ambulance crash threatens the lives of many right on the premises of Seattle Grace.

There's something between George and Izzie. We'll see if it lasts, but here's a cute photo of O'Malley and Stevens from "Kung Fu Fighting."

Who knows. It's hard to define George and Izzie these days. Are they dating or just sort of together? They're both surgeons, though, that much is for sure.

George and Izzie. Their status continues to confound and cause great debate among Grey's Anatomy fans. Where will this love triangle (with these two and Callie Torres) lead?

You don't see George too happy these days, so this photo of him smiling at Izzie comes as a rare sight. Will it last?

Izzie and George may very well be in love... but it does not look like they will last. Or does it? The writers have kept us guessing to this point.

Alex and Izzie talk with a patient. These two had some tense moments in the previous episode. Hopefully all is well.

Call them what you want ... a lot of fans are sick of the story line between George and Izzie. Then again, polls show more viewers than you might think love this couple together.

Izzie Stevens' eyes tell the story. She has no one. Not Denny, not George, not even Really Old Guy. Poor girl.

George, Alex, Meredith, Cristina and Izzie pay their respects to Really Old Guy after he passes away in this mock vigil. It was put together by Izzie because he didn't really have any family or friends left. She's nice.

Izzie looks at her formerly comatose patient in shock. After being really old and non-responsive for a year, he's alive... and he wants to die!