Izzie, Alex and Cristina at George's funeral. We will see this unfold when the new season of Grey's Anatomy airs.
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Alex reacts as Izzie slips away from him, possibly for the last time.
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Is Izzie about to slip away into the afterlife?
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Alex calls for help as Izzie fades into unconsciousness.
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Cristina and Izzie share a moment in "Now or Never."
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Izzie Stevens crashes at the end of "Now or Never." Will she live?
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Alex and Izzie don't know what the best course of action is going forward, and it's hard to blame them.
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Izzie and Alex embrace in the fifth season finale.
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Grey's Anatomy Quotes

We're all going to die. We don't get much say over how or when, but we do get to decide how we're gonna live. So, do it. Decide. Is this the life you want to live? Is this the person you want to love? Is this the best you can be? Can you be stronger? Kinder? More Compassionate? Decide. Breathe in. Breathe out and decide.

Richard

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)