Izzie, Alex and Cristina at George's funeral. We will see this unfold when the new season of Grey's Anatomy airs.
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Alex reacts as Izzie slips away from him, possibly for the last time.
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Is Izzie about to slip away into the afterlife?
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Alex calls for help as Izzie fades into unconsciousness.
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Cristina and Izzie share a moment in "Now or Never."
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Izzie Stevens crashes at the end of "Now or Never." Will she live?
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Alex and Izzie don't know what the best course of action is going forward, and it's hard to blame them.
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Izzie and Alex embrace in the fifth season finale.
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Grey's Anatomy Quotes

[narrating] "At some point, you have to make a decision. Boundaries don't keep other people out, they fence you in. Life is messy, that's how we're made. So you can waste your life drawing lines or you can live your life crossing them. But there are some lines that are way too dangerous to cross. Here's what I know. If you're willing to throw caution to the wind and take a chance, the view from the other side... is spectacular."

MEREDITH

Richard: Chin up. Put your shoulders back, walk proud, strut a little. Don't lick your wounds: celebrate them. The scars you bear are the signs of a competitor. You're in a lion fight, Stevens. Just because you didn't win doesn't mean you don't know how to roar.