With the stress of dealing with both work and home, Derek and Meredith look to be struggling to keep it together.
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Congrats to Cristina! She's been nominated for a Harper Avery!
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The only couple on this list who actually hooked up prior to the series ever starting, Grey's Anatomy kicked off the morning after Meredith and Derek went home from a bar together. Sure, he was married at the time - but that technicality was no match in the end for (sorry we have to say it...) the McDreamiest pairing on all of television.
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Why does Stephanie look so concerned? What did Meredith just say to them on Grey's Anatomy?
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Meredith is serious about finding a new research assistant. "We Gotta Get Out of This Place" is the 16th episode of the show's tenth season.
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Meredith and Cristina look on skeptically in this photo from the Grey's Anatomy episode "You've Got To Hide Your Love Away."
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Cristina eyes Meredith in this scene from "You've Got To Hide Your Love Away." After all these years, we still adore these two.
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It's Meredith's turn to walk down the aisle at April's wedding on Grey's Anatomy. "Get Up, Stand Up" is the 12th episode of the show's tenth season.
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Grey's Anatomy Quotes

Just because we can live without something, it doesn't mean we have to.

Meredith

Derek: I am calling post-it, Zola, Bailey, the tumors on the wall, ferryboat scrub caps. I thought D.C. was everything. I was wrong. You... you're everything. I love you and I'm not going to stop loving you. I can't live without you. I don't want to live without you, and I'm going to do everything in my power to prove it.
Meredith: I can live without you, but I don't want to. I don't ever want to.