Cristina and Meredith talk to Izzie before her wedding to Alex. This episode, the 100th, was one of Grey's Anatomy's best in recent memory.

Rating: 4.8 / 5.0 (48 Votes)
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Show:
Grey's Anatomy
Episode:
Grey's Anatomy Season 5 Episode 22: "What a Difference a Day Makes"
Characters:
Meredith Grey, Cristina Yang, Izzie Stevens
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Grey's Anatomy Photos, Grey's Anatomy Season 5 Episode 22 Photos, Meredith Grey Photos, Cristina Yang Photos, Izzie Stevens Photos
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Grey's Anatomy Season 5 Episode 22 Quotes

Cristina: You slept here?
Callie: I'm awake. What?
Cristina: You slept here? I slept here!
Callie: Um, how? Wait... who? What?
Cristina: I slept in the on call room.
Callie: Oh.
Cristina: I could have been at home in my own bed.
Callie: Sorry.
Cristina: Now I have to work all day, and then I have to be happy maid of honour and get Meredith down the aisle. I'm so tired, 'cause I slept here! 'Cause you wanted to get your freak on with roller skate girl.
Callie: I am sorry. I was gonna, but, we went to dinner and, things didn't... I wasn't in the mood. I had to be here early anyway, to run the ER, so...
Cristina: Oh, you're picking up extra shifts in the ER? So is ah, is Owen not here today?
Callie: Ah, he's here. Oh crap! I'm late. Hey.
Meredith: Hey.
Cristina: BIG DAY! Biggest day of your life!
Meredith: Don't do that! Don't do the peppy maid of honour thing, it's creepy!
Cristina: Really? Good. Wait... is this like the calm before the storm? Do you need me to drug you? Or shave of your eyebrows to numb you into submission?
Meredith: No! I'm fine. It's not the biggest day of my life. It's the biggest day of Izzie's life. I'm excited about the marriage, not some wedding. Anyway, she's the one that's gone all bridezilla.
Cristina: Briiiideeezillaaaaaaaaa...

Meredith: Just a normal day.
Derek: Normal day. Going to work.
Meredith: Just a normal day, that ends in a ceremony in a churchy church.
Derek: This has nothing to do with us, we're just the bride and groom.
Meredith: We're getting married tonight.
Derek: We're getting married tonight (smiles)
Meredith: (smiles back)