Unfortunately for fans of Preston Burke (Isaiah Washington) and Cristina Yang (Sandra Oh) it was not to be in the Season 3 finale of Grey's Anatomy, "Didn't We Almost Have it All."
"I know I haven't been myself lately, but I'm me again, so I was thinking maybe you should sleep over, because the me that I am is horny for the you that you are."
MEREDITH: "Hey." DEREK: "I have a surgery." MEREDITH: "I heard you were the best man." DEREK: "Yeah." MEREDITH: "Maid of honor, best man, kind of perfect." DEREK: "Yeah."