Look out! Jo Harvelle (Alona Tal) is armed with a gun in this scene from Supernatural.
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Sam and Dean are on the case in this scene from Supernatural. It's courtesy of the episode "Bitten."
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Dean just got an important call. Or perhaps he's ordering up a pizza.
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Death and Dean strike a deal on the final episode of 2010. It has to do with Sam's soul.
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Felicia Day is back as Charlie! Who out there does not adore this Supernatural character?!?
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Sam's looking pretty desperate has he sits on the barn floor with his hands tied on this episode of Supernatural.
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Guest star Tim Omundson looks rather relaxed in this Supernatural scene. Dean? Not so much.
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As usual, Sam and Dean have an adventure to deal with this week. The characters are played by Jared Padalecki and Jensen Ackles, respectively.
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Del takes a knife to Dean on the February 26 episode of Supernatural, "Captives."
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The Impala seems like the perfect place for Dean and Sam to have a real chat and get some bro time in. Granted, Dean looks mighty serious, and it is night, but if there’s one thing we’ve learned, these brothers will pull through together no matter what.
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Sam is seen here at a Supernatual fan convention. The scene is from the episode "The Real Ghostbusters."
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Dean holds onto the First Blade. Combined with the Mark of Cain is some real power.
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Supernatural Quotes

You betrayed me? No one in the history of torture's been tortured with torture like the torture you'll be tortured with.

Crowley

Castiel: It's very complex. If the pizza man truly loves this babysitter, why does he keep slapping her rear? Perhaps she has done something wrong.
Dean: Are you watching porn? Why?
Castiel: It was there.
Dean: You don't watch porn in a room full of dudes. And you don't talk about it. Just turn it off. Well now he's got a boner.