Dean and Rufus are seen here on Supernatural. It's a scene from "...And Then There Were None."
Added:

Supernatural Season 6 Episode 16 Quotes

Rufus: We're here. Let's do this. Just like old times.
Bobby: Well, as long as I get to drive.
Rufus: Hell, no.

Rufus: I take it you know each other.
Dean: He's our grandfather.
Rufus: Somebody needs a hug.