Dean is providing protection for the sheriff and the baby inside the halls of the hospital. Against what, is the question. Has the Darkness already arrived or is there something else at play for the premiere?
Dean is taking care of his girl. He probably has a closer relationship with his Impala than any other lady he'll meet in his lifetime. However, if he should have one similar, it's good to know how well cared for she will be.
That is one sexy sneer coming off the face of Dean Winchester! If handing big weapons outside a hospital does that to the man, then they should park the Impala nearby the infirmed more often! Oh shush. Admit it, he's hot.
From the photos, it appears this is the baby daddy, but it's unclear how the sherriff fits into the narrative. She's later in a wheelchair. If she's the mother, she was working very late into her pregnancy!
There's a baby, but neither Sam nor Dean looks very pleased at its appearance. Word is Darkness will take on the form of a specific entity, and a she to boot. Could it start out as a baby, and this one in particular? That wouldn't be a reason to smile.
It's Sam! How we've missed you, Sam. The brothers will be up against the Darkness, a pre-biblical foe who was defeated by God years ago. Sam is shown reaching out to God in the trailer. Can he be of help again? You'd think he might be angry the Winchesters released Darkness after it's already been banished.
Crowley likes to talk to young men in pairs, apparently. When the Winchester brothers aren't around, he'll find another pair of young men to take their place! What do you think he knows about the Darkness? Was she ever mentioned in his social circles?