Sheldon and Amy do a scientific evaluation when she gets turned on by Zach. They determine that she's horny. He wants her to go out with Zach, but instead she tries a hand-holding experiment with Sheldon.
Penny: He wasn't intellectually stimulating enough. Bernadette: Couldn't you just fool around with him and then listen to NPR? Penny: Wouldn't help. Zack couldn't even spell NPR.