In erhaps the most ridiculous situation, Sheldon ends up sleeping in Penny's bed... and somehow this doesn't make the man happy! We'll trade places with you...
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Wolowitz talks to a beautiful girl named Mikayla (Jodi Lyn O'Keefe)... that turns out to be a hooker. Does that bother Wolowitz? Since Leonard and Raj paid... not at all!
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When Wolowitz refuses to leave his hotel room when he can't get over Leslie, Leonard and Raj set him up with a hooker named Mikayla (Jodi Lyn O'Keefe).
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Raj doesn't think there's anything wrong when a beautiful woman, Mikayla (Jodi Lyn O'Keefe) comes up and starts hitting on him. Poor guy doesn't realize she's a prostitute.
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The Big Bang Theory Season 2 Episode 21 Quotes

You know, I'm given to understand that there's an entire city in Nevada devoted specifically to help people like Howard forget their problems. They replace them with new problems such as alcoholism, gambling addiction and sexually transmitted diseases

Sheldon

What exactly does that expression mean, "friends with benefits?" Does he provide her with health insurance?

Sheldon [about Wolowitz and Leslie]