This is a photo from the episode "The Wheaton Recurrence." There's really not much to say about it, is there?
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A picture after Wil Wheaton just bowled as Sheldon prepares to counter.
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Penny and Leonard go bowling and Leoanrd sure does seem to be celebrating something.
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Wil Wheaton calls out Sheldon as the two of them meet in the bowling alley.
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Sheldon has a shirt made that says "The Wesley Crushers" for his bowl off with Wil Wheaton. Get it? No? Wheaton played Wesley on Star Trek.
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Sheldon goes up against Wil Wheaton in the ultimate bowl off between rivals.
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Poor Penny attempts to go bowling as Raj and Wolowitz watch on and drool.
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Sheldon goes up against his nemesis, a characterized version of Wil Wheaton, in bowling on The Big Bang Theory.
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The Big Bang Theory Season 3 Episode 19 Quotes

Wolowitz: Okay forgot giant ants. How about giant rabbits?
Raj: Big or small, I don't like rabbits. They always look like they're about to say something, but they never do.
Sheldon: Rabbits do have a respiratory system that would support great size. And as a side note, they are one of the few animals whose scrotum is on the front of the penis.
Raj: Maybe that's what they want to talk about.

Leonard: If my PE teachers told me this is what I was training for I would have tried a lot harder.
Penny: Do or do not, there is no try.
Leonard: Did you just quote Star Wars?
Penny: I believe I quoted Empire Strikes Back.
Leonard: Oh my God. I'm lying in bed with a beautiful woman who can quote Yoda.