Wil Wheaton returns to The Big Bang Theory on the episode "The 21-Second Excitation." He once again causes problems for the fellas.
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Welcome to comedy, Eliza Dushku. The actress appears as a FBI agent on The Big Bang Theory episode "The Apology Insufficiency."
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Eliza Dushku guest stars on the November 4 episode of The Big Bang Theory. She plays a federal agent.
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Leonard tries to keep an affair secret from Sheldon on "The Irish Pub Formulation." This is a scene from that episode.
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Amy has a request of Sheldon on the episode "The Desperation Emanation." She wants to introduce him to her mother.
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That's Katee Sackhoff and that's George Takei. Both guest star as themselves on the episode "The Hot Troll Deviation."
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Who needs human companionship?!? Not Sheldon, this character hopes, on the episode titled "The Zazzy Substitution."
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How can Sheldon live longer? That's what he tries to figure out on the episode "The Cruciferous Vegetable Amplification."
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TBBT Quotes

Penny, there's only one cookie with something in the middle that solves life's problems, and that's an Oreo. Or a Nutter Butter, if you're in a pinch.

Sheldon

Penny: Here's a question-- as an alien pretending to be human, are you planning to engage in any post-prom mating rituals with Amy?
Sheldon: There are post-prom mating rituals?
Penny: Not always. Unless your date drives a van with an air mattress, then always.
Sheldon: Well, if it's part of the prom experience, then I'm open to it.
Penny: You're kidding.
Sheldon: I may be an alien, but I have urges.If Amy wants to copulate by firing her eggs into space, well, then, I will happily catch them with the reproductive sac on my upper flermin. I'm not the best at reading facial cues, but I can see that you're a little turned on.