RICHARD: "Punching out people on my surgical floor. My head of neurosurgery is punching out people on my surgical floor."
ADDISON: "Put some ice on your hand."
DEREK: "My hand is fine."
RICHARD: "Put the damn ice on your two million dollar a year hand. Now someone tell me what the hell happened."
ADDISON: [pauses] "That was Mark."
RICHARD: "Who’s Mark?"
ADDISON: "He and Derek used to work together back in New York. And they... we... we were all close friends. Until Derek found us in bed together."
RICHARD: "Did you put your weight behind it?"
DEREK: "Yes sir."
RICHARD: [pauses] "Well, alright then."

[Addison hands Meredith hot chocolate]
DEREK: "Juju?"
ADDISON: "Yup."
DEREK: "You just juju'ed Meredith."
ADDISON: "Yes I did. In the spirit of friendship."
DEREK: "Huh."
ADDISON: "What, are we not being friends with Meredith anymore?"
DEREK: "No, no, we are. Meredith and I are friends."
ADDISON: "And you and I are married, so by proxy, Meredith and I are friends."
DEREK: [pauses] "That’s very big of you."
ADDISON: "Yeah."
DEREK: [laughs] "You don’t have to do that. I mean, it's not like I'm going to be friends with, say, Mark."
ADDISON: "Well, neither am I. Now finish your juju before somebody else dies."

PRESTON: "Dr. Shepherd."
DEREK: "Dr. Burke. Hey. We’ve known each other for a while."
PRESTON: "Yes."
DEREK: "We’ve done several successful surgeries together."
PRESTON: "Yes."
DEREK: "Your girlfriend is my ex-girlfriend's best friend."
PRESTON: "Yes."
DEREK: "So, why don’t we call each other by our first names?"
PRESTON: “I don’t think so."
[Later]
ADDISON: "Hey, Preston."
PRESTON: "Good to see you, Addison!"
DEREK: "She gets to call you by your first name and I don't?"
PRESTON: "I like her."
DEREK: "You don't like me?"
PRESTON: "No."

DEREK: "I was indifferent."
ADDISON: "What?"
DEREK: "You know, in New York. Before Mark. I was indifferent towards you."
[pause]
ADDISON: "Yes."
DEREK: "I was absent."
[pause]
ADDISON: "Yes."
DEREK: "I'm partly to blame, for our marriage."
[pause]
ADDISON: "Yes."
DEREK: "I'm sorry... and I'm working on it."
ADDISON: "Okay."

ADDISON: "Are you sad? Depressed? What? It's Christmas, Derek. We love Christmas. Or at least we used to."
DEREK: [pauses] "I'm not saying this to hurt you, or because I want to leave you, because I don't. Meredith wasn't a fling. She wasn't revenge. I fell in love with her. That doesn't go away because I decided to stay with you."

ADDISON: "Why did you bring a trout into the trailer?"
DEREK: "This is dinner!"
ADDISON: "I hate this freaking trailer!"
DEREK: "Fine then. No trout for you."
ADDISON: [broods silently]
DEREK: "Okay, I'll cook the trout outside the trailer."
ADDISON: "I still hate the freaking trailer."

DEREK: "Meredith, I am so sorry. Addison. What are you doing here?"
ADDISON: "Well you'd know if you'd bothered to return any one of my phone calls."
MEREDITH: [confused]
ADDISON: "Hi, I'm Addison Shepherd."
MEREDITH: "Shepherd?"
ADDISON: "And you must be the woman who's been screwing my husband."
MEREDITH: [silence]

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.