Sheldon: Careful, Amy. The friend of my enemy's girlfriend is my enemy.
Amy: Really?
Sheldon: Yes. You're either with me or against me.
Amy: Do you want to take the bus to work?
Sheldon: Maybe there's a third option.

Indiana Jones plays no role in the outcome of the story.

Amy: ... if he weren't in the movie, the Nazis would have still found the ark, taken it to the island, opened it up and all died ... just like they did.
Sheldon: [jaw dropped]
Amy: Let me close that for you.

I'm hoping to put his love of repetition to good use someday.

Amy: So you just got lucky?
Sheldon: Sheldon Cooper doesn't get lucky.
Amy: You and me both.

Sheldon: Now, I know how the African slaves felt. Being dragged from their homes to labor under the yoke of the white man.
Amy: Are you honestly comparing Thanksgiving dinner at the Wolowitz's mom's with one of the greatest tragedies in the history of mankind?
Sheldon: Yes.

Penny: We had one of those silly fake weddings.
Leonard: Penny ... you know those are real, right?
Penny: No, they're not.
Leonard: Yeah, they are.
Penny: No, they're not.
Leonard: Yeah, they are.
Sheldon: He's right.
Amy: They're real.
Penny: But, it didn't seem real.

Amy: It's a beautiful night. Why don't you and I go for a nice walk together?
Sheldon: Everything is just sex with you, isn't it?
Raj: Sheldon, I think you might find the support you're looking for, if you realize that relationships are a give and take. She can only be there for you as much as you are for her.
Amy: Thank you, Rajesh.
Raj: And, Amy, you need to be patient with Sheldon, instead of pressuring him to accept intimacy on your terms.
Amy: You should probably go.

Sheldon: The second I go out of town you throw a Christmas party without me?
Amy: Yeah, kind of.
Sheldon: That's so thoughtful. You guys are the best.

Penny: I can't believe Leonard is spending hundred of dollars on scalped tickets.
Amy: Last week, you spent that on a little dress.
Penny: Yeah, but those tickets only get him into Comic-Con. That dress gets me into anywhere I want.

Amy: I'm sorry, but "Gollum" and "Flakey" are not acceptable.
Sheldon: Well, you don't like "Princess Corncob," you don't like "Fester" -- you're just impossible to please.

Howard: You okay?
Amy: Why? Because my boyfriend's off playing choo-choo with some weirdo?

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?