Amy: Sheldon, there's something else I've been wanting to say, but before I do, I just... I want you to know that you don't have to say it back.I know you're not ready, and I don't want you to say it just because social convention dictates...
Sheldon: I love you, too.
Amy: You said it.
Sheldon: There's no denying I have feelings for you that can't be explained in any other way. I briefly considered that I had a brain parasite. But that seems even more far-fetched. The only conclusion was love.

Not to mention, your acting career is going south like Sherman. Read about it in your book.

I obviously have the flu, coupled with sudden on-set Tourette's Syndrome.

Until you manage to upload your intelligence into a self-sustaining, orbiting satellite equipped with high-speed internet and a cloaking device, you will be dependent on the human race.

Amy: This year's donations may go to, say, the geology department.
Sheldon: Oh dear, not the dirt people.

You don't have to be strong for me. Now let's talk about Priya that man stealing bitch.

I'm regretting my earlier cattiness; she's an absolute delight.

Granted, Penny, your secondary sexual characteristics are reasonably bodacious, but Priya is highly educated, she's an accomplished professional, and she comes from the culture that literally wrote the book on neat ways to have sex. Whereas you on the other hand are a community college dropout who comes from the culture that wrote the book on tipping cows.

Good news! Thanks to you I was able to make a rhesus monkey cry like a disgraced televangelist.

Bernadette: Leonard's really one of a kind.
Amy: Saying that while holding a snowflake is a bit heavy-handed don't you think?

I'm prone to night terrors, so if I wake up kicking and screaming, don't panic. Just pin me down and stroke my hair and I'll be fine.

Amy: I have potential for sexual arousal.
Sheldon: A cross we all must bear.

TBBT Quotes

Penny: Hey, Sheldon, did you change your Wi-Fi password again?
Sheldon: Yes, it's "Penny, get your own Wi-Fi." No spaces.

Sheldon: Why do you have the Chinese character for "soup" tattooed on your right buttock?
Penny: It's not "soup," it's "courage."
Sheldon: No it isn't. But I suppose it does take courage to demonstrate that kind of commitment to soup.
Penny: How'd you see it? You said you wouldn't look.
Sheldon: Sorry. As I told you, the hero always peeks.