Sheldon: Amy, there were Chinese food containers ... in the trash can.
Amy: Poor Leonard.

Your husband's weird and his clothes are ridiculous.

Guys are hitting on us and not just to get to Penny.

Excuse me, but I'm a neurobiologist. I think I'm a little more qualified to understand what's not working in your girlfriend's brain!

Raj: Okay, I have a request to make.
Amy: And now he can talk. I want to cut open your brain and see what the heck is going on in there.

Go away Sheldon is nibbling on my ... 14. Yes!

Sheldon: I have not ruled it out.
Amy: Wow. Talk dirty to me.

They think our relationship is a joke. Are we ever going to have an intimate relationship?

Penny: Vegas here we come.
Bernadette: No husbands. No boyfriends. No rules
Amy: No rules. We're not going to get drunk and have a six-way with the Blue Man Group, are we?
Penny: No.
Amy: So there are some rules.
Bernadette: Okay. No husbands. No boyfriends. Some rules.
Amy: Thank you. VEGAS!

Amy: Missed one. Now your wish can't come true.
Sheldon: Lucky for you because I wished you were dead.

Sheldon: You don't know what it's like to feel completely frustrated. To have a-a desire build up within you and be denied any opportunity for release.
Amy: Yeah. Sounds like a drag.

Amy: All I'm saying is we live in a world where closure isn't always an op...
Sheldon: ...tion. Okay.

TBBT Quotes

Sheldon: Are you still mad about the sperm bank?
Leonard: No!
Sheldon: Do you want to hear an interesting thing about stairs?
Leonard: Not really.
Sheldon: If the height of a single step is off by as little as two millimeters most people will trip.
Leonard: I don't care—two millimeters?! That doesn't seem right.
Sheldon: No, it's true! I did a series of experiments when I was twelve; my father broke his clavicle.

Penny, there's only one cookie with something in the middle that solves life's problems, and that's an Oreo. Or a Nutter Butter, if you're in a pinch.

Sheldon