Sheldon: Amy, there were Chinese food containers ... in the trash can.
Amy: Poor Leonard.

Your husband's weird and his clothes are ridiculous.

Guys are hitting on us and not just to get to Penny.

Excuse me, but I'm a neurobiologist. I think I'm a little more qualified to understand what's not working in your girlfriend's brain!

Raj: Okay, I have a request to make.
Amy: And now he can talk. I want to cut open your brain and see what the heck is going on in there.

Go away Sheldon is nibbling on my ... 14. Yes!

Sheldon: I have not ruled it out.
Amy: Wow. Talk dirty to me.

They think our relationship is a joke. Are we ever going to have an intimate relationship?

Penny: Vegas here we come.
Bernadette: No husbands. No boyfriends. No rules
Amy: No rules. We're not going to get drunk and have a six-way with the Blue Man Group, are we?
Penny: No.
Amy: So there are some rules.
Bernadette: Okay. No husbands. No boyfriends. Some rules.
Amy: Thank you. VEGAS!

Amy: Missed one. Now your wish can't come true.
Sheldon: Lucky for you because I wished you were dead.

Sheldon: You don't know what it's like to feel completely frustrated. To have a-a desire build up within you and be denied any opportunity for release.
Amy: Yeah. Sounds like a drag.

Amy: All I'm saying is we live in a world where closure isn't always an op...
Sheldon: ...tion. Okay.

TBBT Quotes

Raj: Well, to paraphrase Shakespeare: It's better to have loved and lost than to stay home every night and download increasingly shameful pornography.
Penny: Oh... you poor baby.
Raj: What's wrong with me, Penny?
Penny: Nothing, nothing. You know, if we weren't friends - and you hadn't brought up that creepy pornography story - I'd be on you like the speed of light squared on matter to make energy.
Raj: Hey, you totally got that right. E = MC squared.
Penny: I listen. I have no idea what it means, but I listen.

Sheldon: I recently read that during World War Two, Joseph Stalin had a research program to create supersoldiers by having women impregnated by gorillas.
Howard: What a sick use of science.
Raj: Hey, as long as the baby's healthy.
Amy: I wonder if Stalin considered any other animals.
Leonard: Hippos are the deadliest creature. A half-human, half-hippo soldier would be pretty badass.
Howard: Yes, but when they're hungry-hungry, you can stop them with marbles.
Sheldon: Yeah, the correct animal for interspecies supersolider is koala. You would wind up with an army so cute it couldn't be attacked.