Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?
Penny: Damn.
Amy: Well, at least, when we do make love, Sheldon won't be thinking about his mother.

Raj: Let's go see if you fit in my man purse.
Bernadette: Heterosexual, my ass.

Howard: You know, there's a saying we have at NASA. What makes the right stuff so right is that it always comes home.
Bernadette: Stop talking, Howard.

Amy: Goodnight, Painting Penny. Goodnight, Real Penny.
Penny: Goodnight, Real Amy.
Amy: You don't have to say goodnight to Painting Amy, because she's never leaving. Bernadette: Goodnight, Real Penny. Goodnight, Transvestite Penny.

It's okay, I serve soup to poor people.

Bernadette: Because I'm the one that had it towed.
Amy: You?
Bernadette: Didn't see that one coming, did ya?

Penny: He wasn't intellectually stimulating enough.
Bernadette: Couldn't you just fool around with him and then listen to NPR?
Penny: Wouldn't help. Zack couldn't even spell NPR.

Howard's mother had a heart attack because I have sex with him and she can't!

Uh oh, is someone a little blue?

Howard: Two weeks ago I was an astronaut.
Bernadette: Yeah, well, now you're a Smurf. Keep walking.

I'm too small for Twister. And, roller coasters. And sitting with my feet on the floor. Hope you enjoyed the prenatal cigarettes, Mom.

Oh, boo-hoo, you're not going to space!

TBBT Quotes

Penny: Hey, Sheldon, did you change your Wi-Fi password again?
Sheldon: Yes, it's "Penny, get your own Wi-Fi." No spaces.

Sheldon: Why do you have the Chinese character for "soup" tattooed on your right buttock?
Penny: It's not "soup," it's "courage."
Sheldon: No it isn't. But I suppose it does take courage to demonstrate that kind of commitment to soup.
Penny: How'd you see it? You said you wouldn't look.
Sheldon: Sorry. As I told you, the hero always peeks.