Brian: What's it called?
Stewie "Susie".
Brian: [sarcastically] Wow, a song named after a girl. There aren't a million of those already.
Stewie: [annoyed] Name twenty!
Brian: "Rosanna", "Roxanne", "Michelle", "Allison", "Sarah", "Angie", "Brandy", "Mandy", "Gloria", "Cecilia", "Maggie May", "Jessica", "Nancy", "Barbara Ann", "Billie Jean", "Layla", "Lola", "Polly", "Helena", "Jenny from the Block".
Stewie: Name six more.
Brian: "Sherry", "Laura", "Wendy", "Maria", "Peggy Sue", "Minnie the Moocher".
Stewie: Name five more.
Brian: "Tracy", "Jean", "Jane", "Mary Ann", "Eleanor Rigby".
[Short pause; Stewie then throws his guitar on the floor and walks out]
Stewie: Go fuck yourself.

Apollo: I was booked for three hours by "Archibald Meatpants."
Brian: He's...he's dead.
Apollo: Well, either way, I'm getting paid and somebody's getting torn open.

Brian: And somebody replaced Meg's sleeping pills with Alka-Seltzer.
Meg: People are going to miss me when I [long burp].

Brian: Stewie?
Stewie: Yeah?
Brian: It's not your fault.
Stewie: What?
Brian: It's not your fault.
Stewie: I know.
Brian: It's not your fault.
Stewie: (annoyed) I know.
Brian: No Stewie, Stewie. It's not your fault.
Stewie: Don't do this to me man, not you man.
Brian: It's not your fault.
Stewie: Screw you, cut it out man!
Brian: It's not your fault.
Stewie: (cries) Why is it so hard? I didn't know it was going to be so hard. (cries)

Peter: You know they say Chuck Norris is so tough, there's no chin under his beard... there is only another fist.
Brian: That's ridiculous. (Chuck Norris taps him on the back.) Chuck Norris? (A fist comes out of Chuck Norris' beard and punches Brian in the face.)

Stewie: How 'bout we let bygones be bygones,hmm?
Brian: You shot me in both my knees, then lit me on fire, Piss off.

Sgt. Angryman: Congratulations men, you've all passed basic training. I'm proud to call you soldiers. I'm sure you'll do your country proud tomorrow when you are all shipped off, to Iraq.
Brian: What!?
Stewie: Oh don't worry, I'm sure he means Fraggle-Iraq.

You go ahead, I have to make the waffle fries you scream-requested in the car.

(Power goes out, the whole family gasps)
Lois: Oh my god, the power's out.
Chris: What are we gonna do now?
Brian: Well, we could light some candles and read.
(rest of the family pauses before breaking out in laughter)
Chris: Yeah right.
Stewie: Yeah that'd be great.
Peter: Yeah, read the inside of my butt.

Brian: Great idea bringing Stewie to Fenway park Peter.
Peter: Yeah there's no better place for a father and son to really get to know each other then a ball game.
Brian: Ah where is Stewie?
(Cut to Stewie sweating and stuck in the car in the parking lot with all the windows up)
Woman: Is that a baby in there?!
Man: Oh My God... He's gonna miss the game.

Brian: Excuse me Mr. Hemingway. Can I have a beer with you?
Ernest Hemingway: Sure, I love life and all the people in it.
Brian: Thanks and, as a fellow writer, I'd love to talk to you about your craft God if only we can get rid of these damn arms and attach the pen directly to the heart.....
[Hemingway shoots himself]

Jillian: Brian, did you know that Daryl Hannah has one wooden finger?
Brian: Really? Where'd you read that?
Jillian: In Pee-opple Magazine.

Family Guy Quotes

Chris: Mr. Woods. How do I get a girl to like me?
James Woods: Oh Chris, I'm your father, call me "dad".
Chris: Um, okay, dad. How do I get a girl to like me?
James Woods: Well, there's a number of ways Chris. Uh, for example, Kate Moss and I had the same coke supplier, and he threw a punch social one day, and we both happened to be there, and the next thing you know, we're both in the back room, slam bang. I went bareback, babe.
Chris: Wow, she sounds like a class act.
James Woods: No, not at all Chris. No, not at all.

Stewie: (Comes into the bedroom) Lois! Lois! Lois! Lois! Lois! Lois! Mom! Mom! Mom! Mommy! Mommy! Mommy! Mama! Mama! Mama! Ma! Ma! Ma! Ma! Mum! Mum! Mum! Mum! Mummy! Mummy! Mumma! Mumma! Mumma!
Lois: What!?
Stewie: Hi! (Giggling and running out of the room)