Callie: Will you shut up and focus? I need you right now.
Mark: Well I'm a little exhausted, but if you wanna hop on and do all the work ...
Callie: I need to TALK!

Callie: We need to have rules.
Erica: What?
Callie: Rules. We need rules about how we're going to deal with the motherland. Because it's undiscovered country. Maybe... maybe it will be the best vacation either of us have ever had, but it's mysterious, and dark, and ... there should be rules. Oh, and an embassy. And a safe word.
Erica: I'm sorry. What the hell are you talking about?
Callie: Hello? Below the Mason-Dixon line. Of your pants!

Callie: I'm not sure I'm ready to go there.
Erica: Me neither! There's lots of undiscovered territory above the belt. We can take it slow. Maybe just... first base?
Callie: [laughs] Phew! Okay. Phew.
Erica: Finish my wine. I'm going to look at the menu for a minute while your blood pressure drops back down to to normal.
Callie: Erica? Maybe second base too.

Miranda: I don't talk about sex.
Callie: Please. Let's just pretend I never said a single word.
Miranda: I don't talk about sex with anyone, ever. Any kind of sex.
Callie: Bailey I am begging you...
Miranda: Shhhh!!!

Miranda: The va-jay-jay is undiscovered country. It is the mother land. You've never traveled there... You don't know its customs and ways. Now me? I've always wanted to go to Africa. But if I go, I'm going to have to learn a few things first. I'm going to have to prepare. I'll need shots. Bring my own syringes, in case something goes wrong. And I'll wanna know how to get to the embassy.
Callie: Okay now you've lost me.
Miranda: Just talk about it! Not with me. With the other one.

Callie: It's awkward. Because she's a colleague and because she's an attending and because she's a ... she. There's been kissing, but ... no touching and what if I'm not into it? What if I'm horrible at all that stuff... south. I've never been south of the border. With a female. I mean, I've never even been over the ... northern mountains, if you know what I'm saying.
Miranda: [stares in silence]
Callie: We're gonna pretend this didn't happen.

Miranda: They got the nerve to be indignant that they aren't on their specialties anymore. They don't have specialties! They should be grateful they're even allowed in this... Are you listening to me?!
Callie: I'm going on a date with Erica Hahn.

Callie: Stop. You have to stop.
Mark: I can't.
Callie: Seriously. She hates it.
Mark: That's why I can't.

Callie: I guess this makes us virgins, doesn't it.
Erica: I guess in a way it does!
Callie: Vir-gins. Hey, we can be scared together!
Erica: Kinda virgins. And we can be scared together.

Callie: I'm not an experimenter. I don't like to experiment.
Erica: Oh.
Callie: Then you showed up and we did it together and... the experiment was kind of a success!
Erica: Oh... oh!
Callie: Look, I've never done this before. I've never kissed a girl. I'm not sure I even like kissing girls. I don't, actually, like kissing girls. I like kissing one girl. You.
Erica: I don't have anything to compare it to. You're the only woman I've ever kissed.

Callie: Give me two minutes I'll meet you in the third-floor on-call room.
Mark: [points to his pants, then his head] No. We're gonna sit, enjoy a nice meal. I've turned over a new leaf. From now on if you want this, you're gonna get this too.
Callie: Eww.

Erica: I don't... make friends easily. I'm awkward and am bad at small talk and generally don't like people I don't know... but I made friends with you and now you have this thing and that thing is Sloan.
Callie: Are you mad that I'm sleeping with Mark Sloan?
Erica: I'm not mad you're sleeping with Sloan. I'm mad that you didn't tell me that you're sleeping with Sloan. I'm mad at you. Because instead of telling me and admitting that you're one of those girls who goes all pouffy when she gets a boyfriend, you disappear with your thing ... I don't make friends easily.

Grey's Anatomy Quotes

I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old, in your arms. I don't want 48 uninterrupted hours. I want a lifetime. Mmm. Do you see what happens? I say things like that and you fight the urge to run in the opposite direction. It's okay, I understand. I didn't, but now I do, I do. You're just getting started and I've been doing this for a long time now. Deep down, you're still an intern, and you're not ready.

Derek

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith