Eat it, Twilight!

Now I lay me down to sleep, I pray to Castiel to get his feathery ass down here.

You go with Efron. I've got Bieber.

Just because you're blood doesn't mean you're family. You have to earn it.

If you walk out that door, don't you ever come back.

Samuel: This Castiel? You're scrawnier than I pictured.
Castiel: This is a vessel. My true form is approximately the size of your Chrysler Building.
Dean: All right, all right, quit bragging.

I don't trust him. Dude's hiding something. I can feel it and if you weren't Robo-Sam, you'd feel it too.

Dean: God?
Castiel: Yes.
Dean: God?
Castiel: Yes. He isn't in Heaven. He has to be somewhere.
Dean: Try New Mexico. I hear he's on a tortilla.
Castiel: No, he's not on any flatbread.

These aren't vampires, man. These are douche bags.

Sam: Huh.
Dean: Shut it.
Sam: I just said huh.
Dean: I just said shut it.

Dean: Not a word.
Sam: Dude, you just got whaled on by Paris Hilton.

Castiel: The only thing you're going to see out there is Michael killing your brother.
Dean: Well, then I ain't gonna let him die alone.

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean