Dean: Who, whoa, whoa, wait? You two know each other?
Crowley: Not in the biblical sense, more of a business relationship I'd say.
Sam: [to Samuel] You're Crowley's bitch.

If the old man's Kermit, whose hand's up his ass?

I've seen some stupid in my time, but you, you take the crown. Putting Jaws in a fish bowl? How do you think it's going to end?

I don't care if you've got soullessness or the freakin mumps. You know better than this!

I don't trust him. Dude's hiding something. I can feel it and if you weren't Robo-Sam, you'd feel it too.

Samuel: This Castiel? You're scrawnier than I pictured.
Castiel: This is a vessel. My true form is approximately the size of your Chrysler Building.
Dean: All right, all right, quit bragging.

Gramps threw a barbeque and left us off the e-vite list?

Dean: I'm sorry. I'm sorry, one more time. Like I'm five. What do you mean he's got no...
Castiel: Somehow when Sam was resurrected, it was without his soul.

Woman: I'm sitting like this so you'll look at my breasts. I just bought them. I need a lot of attention.
Dean: Good luck with that.

Bobby: Did you know my first girl turned out to be a...
Dean: [hangs up] whoa, no.

Dean: You know what I will have that other one [drink].
Bartender: I thought you were working?
Dean: I'm working up to it.

Castiel: It isn't the Horn of Truth.
Dean: What are you talking about? You were gone for like two seconds. Where did you look?
Castiel: Everywhere.

Supernatural Quotes

You betrayed me? No one in the history of torture's been tortured with torture like the torture you'll be tortured with.

Crowley

Hey, you leave my baby alone! She's got nothing to do with this!

Dean