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Sam: So you're saying having a soul equals suffering?
Dean: Yes, that's exactly what I'm saying.

Sam: What about when there are no more leads for that? I mean are you just supposed to sit there in the dark and suffer, even when there's nothing that can be done at that moment?
Dean: Yes! You sit in the dark and you feel the loss.
Sam: Absolutely, but couldn't I just do all that and have sex with the hippie chick?
Dean: No!

Dean: They're after me!
Sam: Third kind, already? You better run, man. I think the fourth kind is the butt thing.
Dean: Empathy, Sam. Empathy!

You want to be a real boy Pinocchio; you've got to act the part.

Fake it 'til you make it.

Dean: You don't care. You have to care.
Sam: About what exactly?
Dean: About everything!

It's your gigantor body and maybe your brain, but it's not you. So just stop pretending.

Dean: Ok time to go. Now, we can either do this the easy way or the hard way.
Sam: (laughs) What? Soul or not, that's funny.

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