Dean: Are you kidding me? I have been on red alert about Sam and you come for some stupid horn?
Castiel: You asked me to be here and I came.
Dean: I've been asking you for days you d**k!

Bobby: There's a worse case scenario.
Dean: What? Saying he's my co-pilot? Yeah, I know.
Bobby: No, that'd be the other worst case.
Dean: Then what?
Bobby: Maybe it's just Sam.

These aren't vampires, man. These are douche bags.

I'm ok. I killed so many people on the way over here.

Dean: Newsflash Mr. Wizard: "vampires pee."

Dean: Are you wearing glitter?
Kid: I only do it to get laid, man.
Dean: Does it work?

You go with Efron. I've got Bieber.

Dean: Try uh, Lautner.
Sam: He's a werewolf. How do you even know who that is?
Dean: What are you kidding me? That kid is everywhere. It's a friggen nightmare.

Look at this. Watching her sleep, how is that not rape-y?

Bobby: Ok then, lets roll credits on this chick flick. You boys have a safe flight and uh, try some of the local grub. I hear it's exotic.
Dean: Oh yeah, no, definitely, we are. I hear they have an Olive Garden.

You hear that Crowley? That's me flicking my BIC for you.

Now I lay me down to sleep, I pray to Castiel to get his feathery ass down here.

Supernatural Quotes

You're wrong. I am utterly indifferent to sexual orientation. On the other hand, I cannot abide hypocrites like you, Reverend. Tell your flock where your genitals have been before you speak for me.

Castiel

Do you ever get tired of urinating? I'll never get used to it.

Castiel