Tom Tucker: Can I get you some punch?
Thelma: Oh no, see, if you're one of ten million americans like me...
(cuts to a man in a chair)
Man: Like me.
(cuts to a woman on a tennis court)
Woman: Like me.
(cuts back to the community center)
Thelma: ...with a bladder control problem, punch just goes right through you.
(Quagmire comes in)
Quagmire: Ewwwwwww!

(Peter, Joe, Cleveland, and Quagmire are in the Drunken Clam)
Joe: Peter, you're urinating unusually frequently.
Quagmire: Yeah, what gives?
Shamus: If its gale force peein ya be doin, it could mean ya got barnacles on yer prostate. Best have sick bay check below yer decks.
Peter: Wait a minute, are you telling me I need a prostate exam?
Shamus: Aye, and soon, before your rudder jams with flotsam, and your droppin' anchor without an order from the captain. (pauses) How are you liking all of these nautical puns?
Joe: Cute.
Quagmire: Not bad.
Cleveland: Somewhat entertaining.

Peter: Guys, I went to see Dr. Hartman yesterday and he did things to my fanny (Cries)
Cleavland: Peter it's okay.
Peter: No it's not okay, you don't know what it's like.
Cleavland: You're wrong. I too have felt the cold finger of injustice on my insidey parts.
Peter: He did it to you too?
Quagmire: I have something to say. Dr. Hartman violated me as well. I only went in there for a physical slice guinea pig removal, but I turned out to be the guinea pig. With sexual experimentation.
Joe: You guys are a bunch of queers. (Joe rolls away, but then comes back) And so am I. Oh god, it was horrible. I scrubbed and I scrubbed, but damn it, they don't make water hot enough.

Old Lois: Hi, Glen. How's the arthritis?
Old Quagmire: Fine. 'Course, I've gotten a little stiff since you walked in, Giggety gigg... oop, I just pooped a little.
Old Cleveland: Oh... that's... nasty...

Quagmire: Hey Brian, what do you think of my sign?
Brian: "Quagmire's Cross Country Tour." Uh, isn't there an "O" in country?
Quagmire: Nope.

Peter: Sweet, Quagmire! You got a winnebago!
Quagmire: You mean a "Wanna-bang-o"!
Lois: (Sarcastically) Oh, how clever.

As you can see, my family is here and it's game night. We're playing ... sex.

Guys, this is the best dirty book store in town; Family owned, great hours, and lots of parking in the rear!

That's the exit. Of course in this place, every exit's also an entrance.

Peter: Well, my vasectomy is tomorrow.
Cleveland: You poor bastard. Sex is pointless without the potency.
Quagmire: Yeah. You take the venom out of the cobra, and what have you got? You got a... a belt!

Quagmire: Cleveland, how did you end your marriage?
Cleveland: You slept with my wife.

Joan: If you ever left me, I'd cut myself, then I'd cut you. I love you, Glen!
Quagmire: I love you too, insane woman whom I'm having second thoughts about.
Joan: What?!
Quagmire: All right!

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire