Quagmire: Where do you get off?!
Stewie: Pretty much everywhere I hear. Fat man's right -- they're making this easy.

My misguided carnal instincts are the results of being raised by a sexual deviant.

Doctor: How do you feel?
Quagmire's Mom: Horny. Really horny. Could you put him back so I can push him out again?

I don't want to go to jail, but I really want to take credit.

Peter: Jesus, we're going to help you lose your virginity!
Quagmire: Oh god! I love sex!

Jesus: Uh hot ladies. Horny ones. Who, uh, sex on you.
Quagmire: What?
Jesus: Yeah, you know, they come back to your house and sit on your butt.

[meditating] I can be Giggity. I can be Goo.

Sonja: Giggity.
Quagmire: That's my word.

What a surprise, the mugger's never heard of Truman Capote.

Oh my god, he's really hurt bad - you're out of the baseline by the way you're out game's over - but oh my god, Horace is really hurt!

Quagmire: What the hell? Jerome's on your team?
Mort Goldman: That's right! We got to know each other while I was following him around my store!

Joe: Here you go guys, first time in a while I've had wood in my lap.
Quagmire: Are we supposed to laugh at that? Because it's upsetting.

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire